Characterization of the Antibody Response to Acetone-Killed Typhoid Vaccine

Systemic antibody response to nano-size calcium phospate biocompatible adjuvant adsorbed HEV-71 killed vaccine

PURPOSE Since 1980s, human enterovirus-71 virus (HEV-71) is one of the common infectious disease in Asian Pacific region since late 1970s without effective commercial antiviral or protective vaccine is unavailable yet. The work examines the role of vaccine adjuvant particle size and the route of administration on postvaccination antibody response towards HEV-71 vaccine adsorbed to calcium phosp...

can Isolated hepatitis B core antibody in HIV-infected patients response to hepatitis B vaccine help to elucidate the cause?

The relative potencies of heat-killed and acetone-killed vaccines against Salmonella typhimurium in mice.

Mice were immunized against Salmonella typhimurium with graded doses of heat-killed (HK) and acetone-killed (AK) vaccines and then challenged by the oral or intraperitoneal routes with two doses of S. typhimurium. HK and AK vaccines gave good protection against an intraperitoneal challenge, but failed to protect against an oral challenge which is presumably the natural mode of infection. HK vac...

The Immunizing Value of Acetone- and Heat-Killed Vaccines *

Vaccines prepared in various ways have been employed in the study of immunological reactions. Heat-killed vaccines, because of their safety and ease of preparation, have received wide attention, but such vaccines in the study of immunity in mouse typhoid produced with B. enteritidis have not given the degree of resistance desired. Studies of certain types demand the use of a killed vaccine, and...

Formulation of a killed whole cell pneumococcus vaccine - effect of aluminum adjuvants on the antibody and IL-17 response

BACKGROUND Streptococcus pneumoniae causes widespread morbidity and mortality. Current vaccines contain free polysaccharides or protein-polysaccharide conjugates, and do not induce protection against serotypes that are not included in the vaccines. An affordable and broadly protective vaccine is very desirable. The goal of this study was to determine the optimal formulation of a killed whole ce...